I’ve used OpenMediaVault for years and liked it, but I’m just exploring some other options. I’ve got a new system with a Ryzen 370 and 890m iGPU, which Debian is fighting me on getting working. Meanwhile it looks like AMD is treating Ubuntu as a first class citizen for support. Just considering options, maybe Ubuntu plus Cockpit to abstract all the admin stuff?
Since it sounds like you’ll be using it for more than just a NAS, I’d go with TrueNAS, Proxmox or Debian headless (in order of easiest to hardest to install and maintain).